Peptides

MHC II Ea chain (Ea) (52–68) peptide (AbßEp) - 1 mg

$134.00
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  • Cat.Number : AS-61621
  • Availability :
    In stock

Quantity

This is class II MHC Eα chain (Eα) (52–68) peptide (AbβEp). It occupies about 10% of natural Iab

Specifications

Chemistry
Sequence one letter code
  • ASFEAQGALANIAVDKA
Sequence three letter code
  • H-Ala-Ser-Phe-Glu-Ala-Gln-Gly-Ala-Leu-Ala-Asn-Ile-Ala-Val-Asp-Lys-Ala-OH
Molecular Formula
  • C73H118N20O25
Molecular Mass/ Weight
  • 1676
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, mouse, rat, macaque

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Citations

MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b.

J Immunol . 2015 Jan 30 ; 94(5) 2079 | DOI : 10.4049/​jimmunol.1401072.

  • X. Michelet

References

Alternate interactions define the binding of peptides to the MHC molecule Iab

PNAS . 2002 Jun 25 ; 99(13) 8820 | DOI : https://doi.org/10.1073/pnas.132272099

  • X. Lin
  • et al

ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming

Blood . 2005 Jul 01 ; 106(1) 216 | DOI : https://doi.org/10.1182/blood-2005-01-0220

  • E. Segura
  • et al

Peptide dependency of alloreactive CD4+ T cell responses

Intl Immunol . 1999 Mar 01 ; 11(3) 351 | DOI : https://doi.org/10.1093/intimm/11.3.351

  • S. Mendiratta

Presentation of antagonist peptides to naive CD4+ T cells abrogates spatial reorganization of class II MHC peptide complexes on the surface of dendritic cells

PNAS . 2002 Nov 12 ; 99(23) 15012 | DOI : https://doi.org/10.1073/pnas.222463499

  • B. Chmielowski
  • et al