This novel neuropeptide, termed 26RFa, belongs to the RFamide peptide family. The primary structures of human, rat, and frog 26RFa exhibit 80% identity, and the C-terminal octapeptide is fully conserved from amphibians to mammals.
Chartrel, N. et al. PNAS 100, 15247 (2003).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Ser - Gly - Pro - Leu - Gly - Thr - Leu - Ala - Glu - Glu - Leu - Ser - Ser - Tyr - Ser - Arg - Arg - Lys - Gly - Gly - Phe - Ser - Phe - Arg - Phe - NH2