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Peptides

Fibrinogen gamma-Chain (377-395), scrambled - 1 mg

$147.00
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  • Cat.Number : AS-62129
  • Availability :
    In stock

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This is a scrambled sequence of the gamma-fibrinogen amino acids 377 to 395. The original fibrinogen-derived inhibitory peptide attenuates microglia activation and suppresses relapsing paralysis in multiple sclerosis (MS). This scrambled peptide fails to produce these functions.

Specifications

Chemistry
Sequence one letter code
  • KMMISYTFPIERTGLISNK
Sequence three letter code
  • H-Lys-Met-Met-Ile-Ser-Tyr-Thr-Phe-Pro-Ile-Glu-Arg-Thr-Gly-Leu-Ile-Ser-Asn--Lys-OH
Molecular Formula
  • C100H165N25O28S2
Molecular Mass/ Weight
  • 2229.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse

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References

The fibrin-derived γ377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease

J. Exp. Med. . 2007 Mar 05 ; 204(3) 571 | DOI : https://doi.org/10.1084/jem.20061931

  • R. Adams
  • et al