IMG-EN-AS-62189-01.jpg
Peptides

Glu-Glu epitope Tag - 5 mg

$182.00
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  • Cat.Number : AS-62189
  • Availability :
    In production

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This peptide is a 314 to 319 amino acids fragment of the middle T antigen of mouse polymavirus. Glu-Glu epitope peptide is widely used as an epitope tag.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EYMPME
Sequence three letter code
  • H-Glu-Tyr-Met-Pro-Met-Glu-OH
Molecular Formula
  • C34H50N6O12S2
Molecular Mass/ Weight
  • 799
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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Citations

Genetic and biochemical definition of the Hedgehog receptor.

Genes Dev . 2010 Jan 01 ; 24(1) 57 | DOI : 10.1101/gad.1870310

  • X. Zheng

References

Acidic Amino Acids Impart Enhanced Ca2+ Permeability and Flux in Two Members of the ATP-gated P2X Receptor Family

J Gen Physiol . 2007 Feb 26 ; 129(3) 245 | DOI : https://doi.org/10.1085/jgp.200609677

  • D. Samways
  • T. Egan

DNA strand displacement, strand annealing and strand swapping by the Drosophila Bloom's syndrome helicase

Nucl Acid Res . 2007 Feb 15 ; 35(4) 1367 | DOI : https://doi.org/10.1093/nar/gkl831

  • B. Weinert
  • D. Rio

Membrane Topology of the Human Dipeptide Transporter, hPEPT1, Determined by Epitope Insertions

Biochem . 1998 Oct 08 ; 37(43) 15214 | DOI : https://doi.org/10.1021/bi981128k

  • K. Covitz
  • et al

Regulation of Epidermal Growth Factor Receptor Signaling by Phosphorylation of the Ras Exchange Factor hSOS1

J Cell Biol . 1996 Mar 01 ; 271(10) 5871 | DOI : https://doi.org/10.1074/jbc.271.10.5871

  • E. Porfiri
  • F. McCormick