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Peptides  >  Bcl / BAD Peptides  >>  Bax BH3 peptide (55-74), wild type

Product Name Bax BH3 peptide (55 - 74), wild type
STKKLSECLKRIGDELDSNM
Size 1 mg
Catalog # 62266
US$ $121
Purity % Peak Area By HPLC ≥ 95%
Description

This is a 20ľamino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, it can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death.

Storage -20░C
References Shangary, S. et al. Mol. Canc. Ther. 3, 1343 (2004); Shangary, S. et al. Biochem. 41, 9485 (2002).
Molecular Weight 2267.6
Sequence
(One-Letter Code)
STKKLSECLKRIGDELDSNM
Sequence
(Three-Letter Code)
H - Ser - Thr - Lys - Lys - Leu - Ser - Glu - Cys - Leu - Lys - Arg - Ile - Gly - Asp - Glu - Leu - Asp - Ser - Asn - Met - OH
     
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