Transdermal Peptide - 1 mg
- Cat.Number : AS-62066
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This short synthetic peptide facilitates efficient transdermal protein drug delivery through intact skin. Co-administration of the peptide and insulin to the abdominal skin of diabetic rats results in elevated systemic levels of insulin and suppresses serum glucose levels. This peptide creates a transient opening in the skin barrier to enable macromolecular drugs to reach systemic circulation.
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Citations
Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape
Biochem J. . 2011 Apr 15 ; 435(2) 475 | DOI : 10.1042/BJ20101021
- R. Bartz
References
Transdermal protein delivery by a coadministered peptide identified via phage display.
Nat Biotechnol. . 2006 Mar 26 ; 24(4) 455 | DOI : 10.1038/nbt1193
- Y. Chen
- et al