IMG-EN-AS-62732-01.jpg
Peptides

MOG (92–106), mouse, rat - 1 mg

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  • Cat.Number : AS-62732
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This is amino acids 92 to 106 fragment of the myelin oligodendrocyte glycoprotein (MOG) from mouse/rat. Mice with MOG (92–106)-induced experimental autoimmune encephalomyelitis develop extensive B cell reactivity against secondary myelin antigens. Despite the fact that this MOG peptide induces only weak T cell responses, MOG-induced autoimmunity is very severe. This peptide is encephalitogenic in SJL mice, DA rats, and rhesus monkeys.

Specifications

Chemistry
Sequence one letter code
  • DEGGYTCFFRDHSYQ
Sequence three letter code
  • H-Asp-Glu-Gly-Gly-Tyr-Thr-Cys-Phe-Phe-Arg-Asp- His-Ser-Tyr-Gln-OH
Molecular Formula
  • C80H104N21O27S
Molecular Mass/ Weight
  • 1825
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse, rat

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References

A Structurally Available Encephalitogenic Epitope of Myelin Oligodendrocyte Glycoprotein Specifically Induces a Diversified Pathogenic Autoimmune Response

J Immunol . 2004 Jul 01 ; 173(1) 600 | DOI : https://doi.org/10.4049/jimmunol.173.1.600

  • F. Bischof
  • et al