Caloxin 2A1 - 1 mg
- Cat.Number : AS-62604
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Caloxins are extracellular plasma membrane (PM) Ca2+ pump inhibitors. Caloxin 2A1 is a PM Ca2+ pump inhibitor selectively binding to an extracellular domain. It inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts. Caloxin 2A1 is active at an extracellular site, the peptide can simply be added exogenously to inhibit the plasma membrane calcium ATPase (PMCA).
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References
Caloxin: a novel plasma membrane Ca2+ pump inhibitor
Am J Physiol Cell Physiol . 2001 Apr 18 ; 280(4) C1027 | DOI : https://doi.org/10.1152/ajpcell.2001.280.4.C1027
- J. Chaudhary
- et al
Evidence that Ca2+ cycling by the plasma membrane Ca2+-ATPase increases the `excitability' of the extracellular Ca2+-sensing receptor
J Cell Sci . 2003 Apr 15 ; 116(8) 1527 | DOI : https://doi.org/10.1242/jcs.00368
- A. De Luisi
- A. Hofer
Mechanism of action of the novel plasma membrane Ca2+-pump inhibitor caloxin
Cell Calcium . 2003 Apr 01 ; 33(4) 241 | DOI : https://doi.org/10.1016/S0143-4160(02)00207-5
- M. Holmes
- et al