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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Ac)14]-Histone H3 (1-19), H3K14(Ac)

Product Name [Lys(Ac)14] - Histone H3 (1 - 19), H3K14(Ac)
ARTKQTARKSTGG - K(Ac) - APRKQ
Size 1 mg
Catalog # AS-63682
US$ $181
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is Histone H3 acetylated at lysine 14. Histone lysine aetylation is known to play an important role in chromatin-directed gene transcription. A bromodomain 2 of polybromo (a chromatin remodelling protein) preferentially recognizes acetylated lysine of H3.

Storage -20C
References 1, Borra, MT. et al. Biochem. 43:9877 (2004)
2, Charlop-Powers Z. et al. Cell Res. 20:529-538 (2010)
Molecular Weight 2112.4
Sequence
(One-Letter Code)
ARTKQTARKSTGG-K(Ac)-APRKQ
Sequence
(Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys(Ac) - Ala - Pro - Arg - Lys - Gln - OH
Product Citations Adhikary, S. et al. (2015). Selective recognition of H3.1K36 dimethylation/H4K16 acetylation facilitates the regulation of all-trans-retinoic acid (ATRA)-responsive genes by putative chromatin reader ZMYND8 J. Biol. Chem. 291 2664-2681 doi: 10.1074/jbc.M115.679985
     
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