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Peptides  >  C-Peptides  >>  C-Peptide-2, rat

Product Name C - Peptide - 2, rat
EVEDPQVAQLELGGGPGAGDLQTLALEVARQ
Size 0.5 mg
Catalog # 63698
US$ $242
Purity % Peak Area By HPLC ≥ 95%
Description

This rat C-peptide-2 differs from the active human C-peptide by several amino acids, however conserved Glu at positions 3, 11, and 27 is essential for peptide activity. In rat medullary thick ascending limb, C-peptide stimulates Na+,K+-ATPase activity within a physiological concentration range. This effect is due to an increase in Na+,K+-ATPase turnover rate that is most likely mediated by protein kinase C-f phosphorylation of the Na+,K+-ATPase f-subunit.

Storage -20C
References Tsimaratos, M. et al. Diabetolgia 46, 124 (2003).
Molecular Weight 3161.5
Sequence
(One-Letter Code)
EVEDPQVAQLELGGGPGAGDLQTLALEVARQ
Sequence
(Three-Letter Code)
H - Glu - Val - Glu - Asp - Pro - Gln - Val - Ala - Gln - Leu - Glu - Leu - Gly - Gly - Gly - Pro - Gly - Ala - Gly - Asp - Leu - Gln - Thr - Leu - Ala - Leu - Glu - Val - Ala - Arg - Gln - OH
     
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