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Fluorescent Dyes  >  HiLyte™ Fluor Dyes  >>  HiLyte™ Fluor 488 hydroxylamine, HCl salt *single isomer*

Product Name HiLyte™ Fluor 488 hydroxylamine, HCl salt *single isomer*
HiLyte™ Fluor 488 C2 - aminooxyacetamide, HCl salt *single isomer*
Size 1 mg
Catalog # 64348
US$ $325
Description

HiLyte™ Fluor 488 hydroxylamine is a carbonyl-reactive labeling dye, which reacts more readily with aldehydes at physiological pH than other primary amine-containing reagents (such as hydrazides and amines). The reaction of HiLyte™ Fluor 488 hydroxylamine with aldehydes yields oxime ethers, which are stable at physiological conditions. Therefore, HiLyte™ Fluor 488 hydroxylamine can be used to directly detect aldehydes in proteins and DNA. Extinction Coefficient (M-1cm-1): 70,000 Fluorescence quantum yield: 0.91 Fluorescence Life Time (ns): 4.1

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20°C desiccated and protected from light
References D. Boturyn, et al, Tetrahedron, 53, 5485 (1997); J. G. Hecker, et al, ChemmedChem, 3, 1356 (2008); Y. Zeng, et al, Nature methods, 6, 207 (2009).
Molecular Weight 525.94
Spectral Properties Abs/Em = 498/525 nm
Solvent System DMF or DMSO
Product Citations Fabrini R. et al. Biochemistry. 2009 Oct 9
     
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