IMG-EN-AS-64623-1-01.jpg
Peptides

[Lys(Me1)20]-Histone H4 (1-23)-GGK(Biotin)-NH2 - 1 mg

$410.00
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  • Cat.Number : AS-64623-1
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    In stock

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This peptide is Histone H4 (1-23). It is monomethylated at lysine 20 with a C-terminal GG linker, followed by a biotinylated lysine. The monomethylation of histone H4 at lysine 20 is proposed to be a crucial mark for chromosomal memory. It is also very active throughout the cell cycle and is abundant during S phase. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • SGRGKGGKGLGKGGAKRHR-K(Me1)-VLR-GGK(Biotin)-NH2
Sequence three letter code
  • H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys(Me1)-Val-Leu-Arg-Gly-Gly-Lys(Biotin)-NH2
Molecular Mass/ Weight
  • 2842.6
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

Genes Dev . 2008 Aug 01 ; 22(15) 2048 | DOI : 10.1101/gad.476008

  • G. Schotta
  • et al