This peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function. This peptide is labeled with 5-TAMRA on the N-terminus, Abs/Em= 541/568
Storage
-20°C
References
Wang, J. et al. Canc Res60, 1498 (2000); Juin, P. et al. Mol Cell Biol22, 6158 (2002).
Molecular Weight
2137.4
Sequence (One-Letter Code)
5-TAMRA-GQVGRQLAIIGDDINR
Sequence (Three-Letter Code)
5 - TAMRA - Gly - Gln - Val - Gly - Arg - Gln - Leu - Ala - Ile - Ile - Gly - Asp - Asp - Ile - Asn - Arg - OH