IMG-EN-AS-64758-01.jpg
Peptides

Smac/Diablo Peptide [AVPIAQKSE], 5-FAM labeled - 1 mg

$270.00
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  • Cat.Number : AS-64758
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This is a 5-FAM-labeled Smac/Diablo Peptide (Abs/Em=492/518 nm), which serves as a Livin inhibitor. Livin prevents apoptosis and sensitizes Livin-expressing cells to chemotherapy. This peptide has the potential to be used as a therapeutic agent in cancer treatment.

Specifications

Chemistry
Sequence one letter code
  • AVPIAQKSEK-K(5-FAM)-NH2
Sequence three letter code
  • H-Ala-Val-Pro-Ile-Ala-Gln-Lys-Ser-Glu-Lys-Lys(5FAM)-NH2
Molecular Mass/ Weight
  • 1555.8
Properties
Absorbance (nm)
  • 492
Emission (nm)
  • 518
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Livin/melanoma inhibitor of apoptosis protein as a potential therapeutic target for the treatment of malignancy

Mol Cancer Ther . 2007 Jan 01 ; 6(1) 24 | DOI : 10.1158/1535-7163.MCT-06-0443

  • H. Chang
  • A. Schimmer