This is a 5-FAM-labeled Smac/Diablo Peptide (Abs/Em=492/518 nm), which serves as a Livin inhibitor. Livin prevents apoptosis and sensitizes Livin-expressing cells to chemotherapy. This peptide has the potential to be used as a therapeutic agent in cancer treatment.
Chang, H. et al. Mol Cancer Ther6, 24 (2007).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Val - Pro - Ile - Ala - Gln - Lys - Ser - Glu - Lys - Lys(5FAM) - NH2