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Peptides  >  p53 Peptides  >>  [Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human

Product Name [Lys(Ac)373] - p53 (368 - 393), p53 K373(Ac), biotin - labeled, human
Biotin - KGGHLKSK - K(Ac) - GQSTSRHKKLMFKTEGPDSD - NH2
Size 0.25 mg
Catalog # 64865-025
US$ $137
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is tumor suppressor protein, p53 (368-393). There is a biotinylated lyine followed by a GG linker at the N-terminal and an acetylated lysine at lysine 373. Activation of the p53 protein results in the transcription of antiproliferative proteins and induction of apoptosis. The p53 tumor suppressor is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage.

Storage -20C
References Kanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001).
Molecular Weight 3481
Sequence
(One-Letter Code)
Biotin-KGGHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2
Sequence
(Three-Letter Code)
Biotin - Lys - Gly - Gly - His - Leu - Lys - Ser - Lys - Lys(Ac) - Gly - Gln - Ser - Thr - Ser - Arg - His - Lys - Lys - Leu - Met - Phe - Lys - Thr - Glu - Gly - Pro - Asp - Ser - Asp - NH2
     
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