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Peptides  >  Protein Phosphorylation Related Peptides  >>  PDKtide, biotin labeled

Product Name PDKtide, biotin labeled
Biotin - Ahx - KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC
Size 1 mg
Catalog # 64224
US$ $385
Purity % Peak Area By HPLC ≥ 95%
Description

This 39-mer peptide is a biotinylated substrate for phosphatidylinositide-dependent kinase 1 (PDK1). Biotin is linked to the N-terminus of the peptide through an LC (6-carbon linker). PDK1 has a C-terminal pleckstrin homology domain that aims at phosphoinositide lipids on the plasma membrane. It is central to the activating protein kinase B, a protein that mediates biological responses to insulin and growth factors.

Storage -20C
References Berggreen, C. et al. Am J Physiol Endocrinol Metab 296, 635 (2009); Scheid, M. et al. Mol Cell Biol 25, 6 (2005).
Molecular Weight 5110.9
Sequence
(One-Letter Code)
Biotin-Ahx-KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC
Sequence
(Three-Letter Code)
Biotin - Ahx - Lys - Thr - Phe - Cys - Gly - Thr - Pro - Glu - Tyr - Leu - Ala - Pro - Glu - Val - Arg - Arg - Glu - Pro - Arg - Ile - Leu - Ser - Glu - Glu - Glu - Gln - Glu - Met - Phe - Arg - Asp - Phe - Asp - Tyr - Ile - Ala - Asp - Trp - Cys - OH
     
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