Peptides

[Lys(Ac)14/18/23]-Histone H3 (1-24)-GGK(Biotin) - 1 mg

$473.00
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  • Cat.Number : AS-65235-1
  • Availability :
    In stock

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This peptide is histone H3 (1-24) acetylated at Lys14, Lys18, and Lys23, with a C-terminal GG linker followed by a biotinylated Lys. Hyperacetylation of histone H3 plays a role in chromatin structure and transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • ARTKQTARKSTGG-K(Ac)-APR-K(Ac)-QLAT-K(Ac)-A-GGK(Biotin)
Sequence three letter code
  • H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys(Ac)-Ala-Pro-Arg-Lys(Ac)-Gln-Leu-Ala-Thr-Lys(Ac)-Ala-Gly-Gly-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 3149.8
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Synergistic Coupling of Histone H3 Phosphorylation and Acetylation in Response to Epidermal Growth Factor Stimulation

Mol Cell . 2000 Jun 01 ; 5(6) 905 | DOI : https://doi.org/10.1016/S1097-2765(00)80256-7

  • P. Cheung
  • et al