IMG-EN-AS-65199-01.jpg
Peptides

Hyaluronan-Binding Peptide, biotin labeled - 1 mg

$175.00
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  • Cat.Number : AS-65199
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    In stock

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This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.

Specifications

Chemistry
Sequence one letter code
  • GAHWQFNALTVRGGGS-K(Biotin)
Sequence three letter code
  • H-Gly-Ala-His-Trp-Gln-Phe-Asn-Ala-Leu-Thr-Val-Arg-Gly-Gly-Gly-Ser-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 2012.4
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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References

Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking

J Exp Med . 2000 Sep 11 ; 192(6) 769 | DOI : https://doi.org/10.1084/jem.192.6.769

  • M. Mummert
  • et al

Hyaluronan Synthesis Is Required for IL-2-Mediated T Cell Proliferation

J Immunol . 2007 Dec 15 ; 179(12) 179(12) | DOI : https://doi.org/10.4049/jimmunol.179.12.8191

  • C. Mahaffey
  • M. Mummert