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Peptides  >  Apolipoprotein Peptides  >>  Apolipoprotein E (131-169)

Product Name Apolipoprotein E (131 - 169)
GRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRD
Size 1 mg
Catalog # 65188
US$ $335
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is derived from apolipoprotein E (apoE) residues 131-169. ApoE is primarily synthesized by the liver but can also be found in the spleen, kidney, adrenals, gonads, and brain. It is a ligand for low-density lipoprotein receptors and is involved in cholesterol and lipid transport and metabolism. ApoE is associated with peripheral nerve injury and regeneration, immunoregulation, and regulation of cell growth and differentiation. It has also been implicated in the pathogenesis of Alzheimer’s disease (AD), arteriosclerosis, and familial type III hyperlipoproteinemia.

Storage -20°C
References Davignon, J. et al. Arterioscler Thromb Vasc Biol 8, 1 (1988); Mahley, RW. Science 240, 622 (1988).
Molecular Weight 4633.5
Sequence
(One-Letter Code)
GRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRD
Sequence
(Three-Letter Code)
H - Gly - Arg - Leu - Val - Gln - Tyr - Arg - Gly - Glu - Val - Gln - Ala - Met - Leu - Gly - Gln - Ser - Thr - Glu - Glu - Leu - Arg - Val - Arg - Leu - Ala - Ser - His - Leu - Arg - Lys - Leu - Arg - Lys - Arg - Leu - Leu - Arg - Asp - OH
     
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