This peptide is histone H3 (21-43) acetylated at Lys23 with a C-terminal GG linker followed by a biotinylated Lys. Acetylation of histone H3 occurs at Lys14 or Lys23 without preference. Lysine acetylation in histone H3 is associated with transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Garcia, B. et al. Nat Methods4, 487 (2007); Grant, P. et al. J Biol Chem274, 5895 (1999).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Thr - Lys(Ac) - Ala - Ala - Arg - Lys - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Gly - Lys(Biotin) - OH