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Peptides  >  Histones  >  Histone H4 Peptides  >>  [Lys(Ac)8]-Histone H4 (1-25)-GSGSK(Biotin); H4K8(Ac), biotin-labeled

Product Name [Lys(Ac)8] - Histone H4 (1 - 25) - GSGSK(Biotin); H4K8(Ac), biotin - labeled
SGRGKGG - K(Ac) - GLGKGGAKRHRKVLRDNGSGS - K(Biotin)
Size 0.25 mg
Catalog # 65230-025
US$ $132
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is histone H4 (1-25) with acetylation at Lys8. It is biotinylated through a C-terminal GSGSK linker. Acetylation at Lys8 is crucial to the recruitment of the SWI/SNF (switch/sucrose non-fermenting) chromatin-remodeling complex through the bromodomain-containing protein BRG1 for transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Kurdistani, S. and M. Grunstein Nat Rev Mol Cell Biol 4, 276 (2003).
Molecular Weight 3274.8
Sequence
(One-Letter Code)
SGRGKGG-K(Ac)-GLGKGGAKRHRKVLRDNGSGS-K(Biotin)
Sequence
(Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys(Ac) - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - Leu - Arg - Asp - Asn - Gly - Ser - Gly - Ser - Lys(Biotin) - OH
     
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