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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Ac)56]-Histone H3 (44-63)

Product Name [Lys(Ac)56] - Histone H3 (44 - 63)
GTVALREIRRYQ - K(Ac) - STELLIR
Size 0.25 mg
Catalog # 65204-025
US$ $70
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is histone H3 (44-63) with acetylation at Lys56. Lys56 acetylation occurs during premeiotic and mitotic S phases and persists through DNA damage repair and is catalyzed by the Rtt109-Vps75 histone acetyltransferase (HAT) complex. A deficiency of acetylated Lys56 in histone H3 is implicated in spontaneous chromosome breaks during mitosis, suggesting that this modification is important for replisome integrity and DNA replication.

Storage -20C
References Han, J. et al. J Biol Chem 282, 28587 (2007); Schneider, J. et al. J Biol Chem 281, 37270 (2006).
Molecular Weight 2444.9
Sequence
(One-Letter Code)
GTVALREIRRYQ-K(Ac)-STELLIR
Sequence
(Three-Letter Code)
H - Gly - Thr - Val - Ala - Leu - Arg - Glu - Ile - Arg - Arg - Tyr - Gln - Lys(Ac) - Ser - Thr - Glu - Leu - Leu - Ile - Arg - OH
     
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