Peptides

Thrombospondin (TSP-1)-derived Peptide; binding motif for CD36 - 1 mg

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  • Cat.Number : AS-65371
  • Availability :
    In stock

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This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.

Specifications

Chemistry
Sequence one letter code
  • CSVTCG (S-S Bonded)
Sequence three letter code
  • H-Cys-Ser-Val-Thr-Cys-Gly-OH (S-S Bonded)
Molecular Formula
  • C20H34N6O9S2
Molecular Mass/ Weight
  • 566.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Bovine

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References

Identification and characterization of a tumor cell receptor for CSVTCG, a thrombospondin adhesive domain

J Cell Biol . 1993 Jan 15 ; 120(2) 513 | DOI : https://doi.org/10.1083/jcb.120.2.513

  • G. Tsuzynski
  • et al

Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding

Biochem Biophys Res Commun . 1992 Feb 14 ; 182(3) 1208 | DOI : https://doi.org/10.1016/0006-291X(92)91860-S

  • A. Asch
  • et al

The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threoninecysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer

Histol Histopathol . 2001 Apr 01 ; 16(2) 345 | DOI : 10.14670/HH-16.345

  • T. Wakiyama
  • et al