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Peptides > Cyclic Peptides > Disulfide Cyclized Peptides >> Cyclo (-GRGDSP)

Product Name	Cyclo ( - GRGDSP) GRGDSP, N to C cyclized
Size	1 mg
Catalog #	AS-61110
US$	$61
Purity	% Peak Area By HPLC ≥ 95%
Description	This cyclic peptide is a potent vasodilator. It is more powerful than the linear GRGDSP (Cat# 22945, 22946) in changing the vascular tone of arterioles isolated from rat cremaster muscle.
Detailed Information	Datasheet Material Safety Data Sheets (MSDS)
Storage	-20°C
References	Mogford, JE. et al. Circulation Res. 79, 821 (1996).
Molecular Weight	569.6
Sequence (One-Letter Code)	GRGDSP, N to C cyclized
Sequence (Three-Letter Code)	Cyclo( - Gly - Arg - Gly - Asp - Ser - Pro)
Product Citations	Burch, ML. et al. (2013). Thrombin-mediated proteoglycan synthesis utilizes both protein-tyrosine kinase and serine/threonine kinase receptor transactivation in vascular smooth muscle cells. J Biol Chem 288, 7410. doi: 10.1074/jbc.M112.400259. Mukhatyar, V. et al. (2011). Role of fibronectin in topographical guidance of neurite extension on electrospun fibers. Biomaterials doi:10.1016/j.biomaterials.2011.02.015. Kong, F. et al. (2009). Demonstration of catch bonds between an integrin and its ligand. J Cell Biol 185, 1275. Kirkpatrick, ND. et al. (2007). Live imagine of collagen remodeling during angiogenesis. AJP-Heart 292, H3198. Nadanaka, S. et al. (2001). Occurrence of oligosialic acids on integrin α5subunit and their involvement in cell adhesion to fibronectin. J Biol Chem 276, 33657.

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