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Peptides  >  Cyclic Peptides  >   Disulfide Cyclized Peptides  >>  Oxytocin

Product Name Oxytocin
CYIQNCPLG - NH2 (Disulfide bridge: 1 - 6)
Size 5 mg
Catalog # AS-24275
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

Oxytocin (OT) is a 9-amino acid peptide that is synthesized primarily in the hypothalamic neurons, specifically the magnocellular oxytocin neurons in the supraoptic and paraventricular nuclei and is secreted by the posterior pituitary gland. It is also secreted from other tissues, such as the ovaries and testes. Circulating OT is important during parturition and lactation. In the pregnant uterus, oxytocin and the oxytocin receptor play a major part for uterine contractility and the induction of labor. OT is also involved in complex social behaviors such as affiliation, sexual behavior, social recognition, stress buffering, aggression, and trust.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Sabatier, N. et al. J Neurosci 23, 10351 (2003)
Luck, M. et al. J Endocrinol 114, 423 (1987)
Richter, O. et al. Arch Gynecol Obstet 269, 16 (2003)
Hirst, J. et al. Endocrinol 124, 225 (1990)
Szeto, A. et al. Psychosom Med (2012), doi: 10.1097/PSY.0b013e31821df0c2
Molecular Weight 1007.2
Sequence
(One-Letter Code)
CYIQNCPLG-NH2 (Disulfide bridge: 1-6)
Sequence
(Three-Letter Code)
H - Cys - Tyr - Ile - Gln - Asn - Cys - Pro - Leu - Gly - NH2 (Disulfide bridge: 1 - 6)
Product Citations Beyer, C. et al. (2010). Angiotensin IV elevates oxytocin levels in the rat amygdala and produces anxiolytic-like activity through subsequent oxytocin receptor activation. Psychopharmacol 209, 303.
     
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