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Recombinant Proteins  >  α-Synuclein & β-Synuclein  >>  EndoClear™* Human Recombinant alpha-Synuclein Protein

Product Name EndoClear™* Human Recombinant alpha - Synuclein Protein  NEW
less than 0.1 EU per μg protein
Size 1000 µg
Catalog # AS-55555-1000
US$ $551
Purity Greater than 95% as determined by SDS-PAGE.
Description

Full-length Recombinant human alpha-synuclein (GenBank Accession # NP_000336) was expressed in E. coli., and purified from bacterial lysate using proprietary method. Endotoxin was further removed by proprietary technique. Molecular weight of the recombinant α-synuclein protein is 14.5 kDa.

α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.

EndoClearTM human α-synuclein recombinant protein (<0.1EU/ug protein) is available in various sizes: AS-55555-100, AS-55555-500, AS-55555-1000. For even lower endotoxin requirements, we offer EndoClearTMPlus (<0.001EU/ug protein) AS-56081-100 and AS-56081-500
* previously referred to as: EndoFree human α-synuclein recombinant protein

find out more EndoClear™ & EndoClear™Plus alpha Synuclein protein

Images EndoClear™* Human Recombinant alpha-Synuclein Protein
Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage The purified α-synuclein is supplied as lyophilized powder nearly salt free. Store at 2-4 ºC for immediate use within 1-2 weeks or at –80 ºC for up to 12 months.
References 1. Rivers, R. et al. Protein Science 17, 887-898 (2008).
2. Bruening, W. et al. Cancer. 88, 9, 2154-2163 (2000).
3. George M. J. Genome Biology 3, 1, 1-6 (2001).
4. Latawiec, D. et al. PloS ONE 5, 2, 1-8 (2010).
     
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