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Peptides  >  Growth Factors  >>  EGF Receptor Substrate 2 [DADE-pY-LIPQQG], Biotinylated
Product Name EGF Receptor Substrate 2 [DADE - pY - LIPQQG], Biotinylated
Biotin - DADE - pY - LIPQQG
Size 1 mg
Catalog # AS-29972-1
US$ $203
Purity % Peak Area By HPLC ≥ 95%
Description

The unlabeled phosphopeptide is an excellent substrate for mammalian protein tyrosine phosphatase 1B (Km = 3.9 µM) and Yersinia PTP. The sequence is derived from an autophosphorylation site (Tyr992) of EGFR. The unlabeled peptide is used to assay PTB based on marked fluorescence increase upon the removal of the phosphate group (Em = 305 nm and Ex = 282 nm).
Storage -20°C
References Ref: Ukkola, O. and MJ. Santaniemi, Intern. Med. 251, 467 (2002); Sarmiento, M. et al. J. Biol. Chem. 273, 26368 (1998); Zhang, ZY. et al. Anal. Biochem. 211, 7 (1993).
Molecular Weight 1556.6
Sequence
(One-Letter Code)		 Biotin-DADE-pY-LIPQQG
Sequence
(Three-Letter Code)		 Biotin - Asp - Ala - Asp - Glu - pTyr - Leu - Ile - Pro - Gln - Gln - Gly - OH
     
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