Dye-Labeled ß-Amyloid Peptides – Full Spectrum of Possibilities


Combining one of the world’s largest collections of amyloid peptides with proprietary expertise in detection technology, AnaSpec offers an unmatched array of labeled amyloid peptides. Labeling options include biotin as well as a full spectrum of fluorescent dyes, ranging from classic dyes like FAM and TAMRA to AnaSpec’s proprietary HiLyte™ Fluor series of high-performance dyes.  Discover the possibilities.

Figures 1 & 2. Absorption and emission spectrum of the different fluorophore-labeled Aß (1-42).

Labeled ß-Amyloid Peptides

HiLyte™ Fluor-Labeled

AMCA-Labeled

FAM-Labeled

TAMRA-Labeled

Biotin-Labeled

Listed below are some of our labeled amyloid peptides (selected literature citations listed):

Product

ex/em (nm)

ß-Amyloid
(1-28)

ß-Amyloid
(1-40)

ß-Amyloid
(1-42)

Unlabeled

N/A

24231 (0.5mg)

24232 (1 mg)

Kanekiyo, T. et al. PNAS USA 104, 6412 (2007); Osada, Y. et al. J. Biol. Chem. 280, 8596 (2005).

24235 (0.5mg)

24236 (1 mg)

Cho, S. and Y. Hu, Exp. Neurol. 203, 274 (2007); Lee, S. et al. Protein Sci. 16, 723 (2007).

24224 (0.5mg)

20276 (1 mg)

Nelson, TJ. & DL Aklon, J. Biol. Chem. 10.1074/jbc.M705558200 (2007); Osada, Y. et al. J. Biol. Chem. 280, 8596 (2005).

Scrambled sequence

N/A

 

24625 (0.5mg)

24626 (1 mg)

Ji, Y. et al. J. Alzheimer’s Dis. 3, 23 (2001).

25382 (0.5mg)

25383 (1mg)

Shaked, GM. et al. FASEB J. 20, 1254 (2006); Puzzo, D. et al. J. Neurosci. 25, 6887 (2005).

Reversed sequence

N/A

 

22817 (0.5mg)

22818 (1mg)

Kajkowski, EM. et al. J. Biol. Chem. 276, 18748 (2001).

27276-01 (0.1mg)

27275 (0.5mg)

27276 (1mg)

Widenbrant, MJO. et al. Biophys. J. 91, 4071 (2006); Boyd-Kimball, D. et al. Brain Res. 1044, 206 (2005).

Biotin

N/A

60459 (0.1mg)

23512-01 (0.1mg)

23511-05 (0.5mg)

23512 (1mg)

Inaba S. et al. J. Pept. Res. 65, 485 (2005).

23524-01 (0.1mg)

23523-05 (0.5mg)

Kanekiyo, T. et al. Proc. Natl. Acad. Sci. USA 104, 6412 (2007).

Lys-Biotin

(C-terminus)

N/A

 

61483-01 (0.1mg)

61483-05 (0.5mg)

23528-01 (0.1mg)

23527 (0.5mg)

Biotin-LC

N/A

 

24645-01 (0.1mg)

24648 (0.5mg)

24645 (1mg)

Li, Q. et al. BMC Neurosci. 5, 21 (2004).

24641-01 (0.1mg)

24640 (0.5 mg)

Nelson, TJ. and DL Aklon, J. Biol. Chem. 10.1074/jbc.M705558200 (2007).

Lys-Biotin-LC

(C-terminus)

N/A

 

23518-01 (0.1mg)

23517 (0.5mg)

61484-01 (0.1mg)

AMCA-X

354/442

60460 (0.1mg)

60487-01 (0.1mg)

60475-01(0.1mg)

FAM (Carboxyfluorescein)

494/521

60759-01 (0.1 mg)

60759 (0.5 mg)

23514-01 (0.1mg)

23513-05 (0.5mg)

Wakabayashi, M. and K. Matsuzaki, J. Mol. Biol. 371, 924 (2007).

23526-01 (0.1mg)

23525-05 (0.5mg)

Saavedra, L. et al. J. Biol. Chem. 10.1074/jbc.M701823200 (2007); Choucair, A. et al. Biochim. Biophys. Acta 1768, 146 (2007).

HiLyte™ Fluor 488

503/528

60466-01 (0.1mg)

60491-01 (0.1mg)

60479-01 (0.1mg)

HiLyte™ Fluor 555

551/567

60468-01 (0.1mg)

60492-01 (0.1mg)

60480-01 (0.1mg)

HiLyte™ Fluor TR

584/608

60464-01 (0.1mg)

60490-01 (0.1 mg)

 

TAMRA

544/572

60461-01 (0.1mg)

60488-01 (0.1mg)

60476-01 (0.1mg)

Rodent sequence

N/A

 

25380 (0.5mg)

25230 (1 mg)

61718-01 (0.1 mg)

61718-05 (0.5 mg)

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