T-Cell Epitopes OVA (323-339), HEL (46-61) & More


Peptides, used individually, as pools or as libraries, have been used extensively as vaccines in stimulating T cells.1 Once bound to MHC (major histocompatibility complex) molecules, these T cells epitopes can activate CD4 or CD8 T cells.1, 2

AnaSpec has been a manufacturer of these peptides for more than ten years. Use of these peptides has been reported in respected journals such as the Journal of Biological Chemistry since 1997.3 A sample list of other references are listed below.

Table 1. A sample list of AnaSpec T cell epitopes

Product

Cat#

MHC

OVA (323-339)

27024 (1 mg)
27025 (5 mg)

Class II

OVA (323-339), amide

62571-1 (1 mg)
62571-5 (5 mg)

Class II

HEL (46-61)

60504-1 (1 mg)

Class II

HA (110-120)

61019 (1 mg)

Class II

OVA (257-264)

60193-1 (1 mg)
60193-5 (5 mg)

Class I

OVA (257-264), amide

62572-1 (1 mg)
62572-5 (5 mg)

Class I

MSL8, [Met256]-OVA (257-264)

62573-1

Class I

HSV - gB2 (498 - 505)

61708

Class I

VSV-8

60785

Class I

Ndufa (461-468)

61668

Class I

Full Listing of all T cell epitopes

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Related Products and Service:
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     EBV Control Peptide Pool
     Influenza Virus Control Peptide Pool
MOG peptides and ELISA kits
Peptide Synthesis Service

References:

  1. Kiecker, F. et al. Human Immunol. 65, 523 (2004).
  2. Robinson, JH. And AA. Delvig, Immunology 105, 252 (2002).
  3. Ben-Shahar, S. et al. J. Biol. Chem. 272, 21060 (1997).
  4. Sato, N. et al. Proc. Natl. Acad. Sci. 104, 588 (2007).
  5. Galibert, L. et al. J. Biol. Chem. 280, 21955 (2005).
  6. Komlosh, A. et al. J. Biol. Chem. 276, 30050 (2001).
  7. Ben-Shahar, S. et al. J. Biol. Chem. 274, 21963 (1999).
  8. Stachowiak, AN. et al. J. Immunol. 177, 2340 (2006).
  9. Garrod, KR. et al. J. Immunol. 177, 863 (2006).
  10. Baekkevold, ES. et al. J. Exp. Med. 201, 1045 (2005).
  11. Kwa, S. et al. J. Immunol. 201, 1045 (2005).
  12. Seroogy, CM. et al. J. Immunol. 173, 79 (2004).
  13. Dorsam, G. et al. J. Immunol. 171, 3500 (2003).
  14. Bard, F. et al. PNAS. 100, 2023 (2003).