AnaSpec is pleased to announce the release of Mant-ATP and
Mant-ATP and Mant-GTP are the fluorescent analogs of ATP and
GTP where either the ribose 2’-hydroxy or the 3’-hydroxy group is esterified
by the fluorescent methylisatoic acid (Figure 1). The fluorescence
quantum yield of Mant fluorophore is 0.2 in water, which increases significantly
in nonpolar solvents or upon binding to most proteins. The highly environmentally
sensitive fluorescence of Mant makes Mant-ATP and Mant-GTP useful probes for
directly detecting nucleotide-protein interactions at Ex/Em=355/448 nm.
With >95% purity, AnaSpec’s Mant-ATP and Mant-GTP offer
cost-effective value without compromising performance.
Figure 1. Structures of Mant-ATP (left) and Mant-GTP (right).
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