7-Hydroxycoumarin-3-carboxylic acid is one of the most popular blue fluorophores for labeling proteins and nucleic acids mostly through the in situ formation of its succinimidyl ester (81206). This coumarin is also increasingly used to label peptides, nucleotides and carbohydrates.
Higai K, et al. (1999). A fluorometric assay for glycosyltransferase activities using sugars aminated and tagged with 7-hydroxycoumarin-3-carboxylic acid as substrates and high performance liquid chromatography. Biol Pharm Bull 22, 333-8; Li H, et al. (1996). Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cells. J Cell Biol 134, 1019-30.
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