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Peptides  >  Amyloid Peptides  >  Beta-Amyloid (1-40) and Related Peptides  >>  Beta-Amyloid (1-40) HFIP, Human

Product Name Beta - Amyloid (1 - 40) HFIP, Human
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Size 1 mg
Catalog # 64128-1
US$ $303
Purity % Peak Area By HPLC ≥ 95%
Description

Removal of any pre-existing structures in lyophilized stocks of Aβ-peptide is the critical initial step for controlled aggregation studies. HFIP has been shown to break down β-sheet structure, disrupt hydrophobic forces in aggregated amyloid preparations, and promotes α-helical secondary structure. HFIP treatment of lyophilized Aβ-peptide resulted in a dense, homogeneous preparation of unaggregated peptide and samples can be stored as peptide films.

Storage -20C
References Ref: Stine, W.B. et al. J. Biol. Chem., 278, 11612 (2003).
Molecular Weight 4329.9
Sequence
(One-Letter Code)
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Sequence
(Three-Letter Code)
H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - OH
Product Citations Palmer, J. et al. Am J Pathol 175, 262 (2009).
Kim, J. R. et al. Protein Sci 13, 2888 (2004).
     
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