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Peptides  >  Amyloid Peptides  >  Beta-Amyloid (1-42) and Related Peptides  >>  Scrambled-beta-Amyloid (1-42), Human

Product Name Scrambled - beta - Amyloid (1 - 42), Human
AIAEGDSHVLKEGAYMEIFDVQGHVFGGKIFRVVDLGSHNVA
Size 0.5 mg
Catalog # AS-25382
US$ $264
Purity % Peak Area By HPLC ≥ 95%
Detailed Information Datasheet
Storage -20°C
Molecular Weight 4514.1
Sequence
(One-Letter Code)
AIAEGDSHVLKEGAYMEIFDVQGHVFGGKIFRVVDLGSHNVA
Sequence
(Three-Letter Code)
H - Ala - Ile - Ala - Glu - Gly - Asp - Ser - His - Val - Leu - Lys - Glu - Gly - Ala - Tyr - Met - Glu - Ile - Phe - Asp - Val - Gln - Gly - His - Val - Phe - Gly - Gly - Lys - Ile - Phe - Arg - Val - Val - Asp - Leu - Gly - Ser - His - Asn - Val - Ala - OH
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Davis, R. et al. (2011). Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation. Mol Neurodegeneration 6, 10.
Gamba, P. et al. (2011). Interaction between 24-hydroxycholesterol, oxidative stress and amyloid-β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime. Aging Cell DOI: 10.1111/j.1474-9726.2011.00681.x.
Miners, J. et al. (2011). Neprilysin protects against cerebral amyloid angiopathy and Aβ-induced degeneration of cerebrovascular smooth muscle cells. Brain Pathol DOI: 10.1111/j.1750-3639.2011.00486.x.
Vargas, T. et al. (2010). Gelsolin restores Aβ-induced alterations in choroid plexus epithelium. J Biomed Biotechnol doi:10.1155/2010/805405.
De Felice, FG. et al. (2009). Protection of synapses against Alzheimer’s-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers. PNAS 106, 1971 (2009).
Garcia-Osta, A. et al. (2009). Amyloid beta mediates memory formation. Learn Mem 16, 267.
Hoos, M. et al. (2009). Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in vitro. Biochem 48, 4720.
Shaked, GM. et al. (2006). Aß induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597–624). FASEB J 20, 1254.
Maloney, MT. et al. (2005). β -secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid β : a feedforward mechanism for Alzheimer’s Disease. J Neurosci 25, 1131.
Puzzo, D. et al. (2005). Amyloid-β peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity. J Neurosci 25, 6887.
Kumar-Singh, S. et al. (2002). In vitro studies of flemish, dutch, and wild-type β-amyloid provide evidence for two-staged neurotoxicity. Neurobio Dis 11, 330.
Lue, LF. And DG. Walker (2002). Modeling Alzheimer's disease immune therapy mechanisms: Interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide. J Neurosci Res 70, 599.
     
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