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Peptides  >  Ghrelins and Obestatins  >>  Biotin-Ghrelin, human

Product Name Biotin - Ghrelin, human
Biotin - GS - S(n - octanoyl) - FLSPEHQRVQQRKESKKPPAKLQPR
Size 1 mg
Catalog # AS-29391
US$ $363
Purity % Peak Area By HPLC ≥ 95%
Description

This Ghrelin peptide is biotinylated at the peptide N-terminus. Ghrelin is an appetite stimulating peptide hormone secreted by stomach P/D1-type cells in humans and circulates in the bloodstream during fasting conditions. Enzymatically n-octanoylated Serine3 of this 28-amino acid Ghrelin is the endogenous ligand specific for growth hormone secretagogue receptor 1a (GHSR1a). The GHSR1a receptor appears to be dedicated to Ghrelin and is widely expressed in different tissues.

Storage -20C
References Kojima, M. et al. Nature 402, 656 (1999), doi:10.1038/45230
Yang J., et. al. Cell 132, 387 (2008). doi: 10.1016/j.cell.2008.01.017
Kojima, M. et. al. Physiol Rev 85, 495 (2005), doi: 10.1152/physrev.00012.2004
Perello, M. & Dickson, SL. J Neuroendocrinol 27, 424 (2015), doi: 10.1111/jne.12236
Molecular Weight 3597.2
Sequence
(One-Letter Code)
Biotin-GS-S(n-octanoyl)-FLSPEHQRVQQRKESKKPPAKLQPR
Sequence
(Three-Letter Code)
Biotin - Gly - Ser - [Ser(n - octanoyl)] - Phe - Leu - Ser - Pro - Glu - His - Gln - Arg - Val - Gln - Gln - Arg - Lys - Glu - Ser - Lys - Lys - Pro - Pro - Ala - Lys - Leu - Gln - Pro - Arg - OH
     
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