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| Product Name |
Protease - Activated Receptor - 4, PAR - 4 Agonist, amide, murine |
| Size |
1 mg |
| Catalog # |
60778 |
| US$ |
$55 |
| Purity |
% Peak Area By HPLC ≥ 95% |
| Description |
The family of at least seven transmembrane G protein coupled receptors includes at least four receptor subtypes (PAR1, PAR2, PAR3, PAR4). PAR4 activating peptides, GYPGKF-NH2 and AYPGKG-NH2, produce concentration dependent contractile effects on the muscle. |
| Storage |
-20°C |
| References |
Ref: Fang, J. et al. Blood 106, 2671(2005); Mulč, F. et al. Gut. 53, 229 (2004); Sekiguchi, F. et al. Drug Design Rev. 1, 287 (2004); Faruqi, T. et al. J. Biol. Chem. 275, 19728 (2000); Greenberg, D. Biochem. 42, 2702 (2003); Henriksen, R. and V. Hanks, Arterioscler. Thromb. Vasc. Biol. 22, 861 (2002); Gui, Y. et al. Am. J. Physiol. Renal. Physiol. 285, 95 (2003). |
| Molecular Weight |
666.8 |
Sequence
(One-Letter Code) |
GYPGKF-NH2 |
Sequence
(Three-Letter Code) |
H - Gly - Tyr - Pro - Gly - Lys - Phe - NH2 |
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