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Peptides  >  Luteinizing Hormone-Releasing Hormones and Related Peptides  >>  Cetrorelix Acetate, Cetrotide
Product Name Cetrorelix Acetate, Cetrotide
Size 1 mg
Catalog # 60869
US$ $181
Purity % Peak Area By HPLC ≥ 95%
Description

A highly modified luteinizing hormone-releasing hormone (LHRH) decapeptide with a terminal amide group, this peptide is a LHRH antagonist. It regulates the expression of Galphas and Galphai protein subunits and adenylate cyclase activity in ovary, breast and pituitary. Cetrorelix competitively inhibits LHRH receptor in the pituitary gland to suppress ovarian and testicular functions.
Detailed Information Material Safety Data Sheets (MSDS)
Storage -20°C
References Ref: Collado, B. et al. Intl. J. Oncol. 24, 725 (2004); Schwahn, M. et al. Drug Metabolism and Disposition. 28, 10 (2000).
Molecular Weight 1431.2•60
Sequence
(Three-Letter Code)		 Ac - {D - Ala[3 - (2 - naphthyl)]} - [D - Phe(4 - Cl)] - {D - Ala[3 - (3 - pyridyl)]} - Ser - Tyr - (D - Cit) - Leu - Arg - Pro - D - Ala - NH2 • Acetate
Product Citations Chou, C. et al. J. Clin. Endocrinol. Metab. 88, 3806 (2003).
     
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