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Peptides  >  OVA Peptides  >>  OVA (257-264)

Product Name OVA (257 - 264)
Size 5 mg
Catalog # AS-60193-5
US$ $198
Purity % Peak Area By HPLC ≥ 95%

This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.

Detailed Information Datasheet
Storage -20°C
References Werlen, G. et al. Nature 406, 422 (2000); Maecker, H. et al. J. Immunol. 161, 6532 (1998).
Molecular Weight 963.2
(One-Letter Code)
(Three-Letter Code)
H - Ser - Ile - Ile - Asn - Phe - Glu - Lys - Leu - OH
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Larghi, P. (2012). The p50 subunit of NF-κB orchestrates dendritic cell lifespan and activation of adaptive immunity PLoS One doi: 10.1371/journal.pone.0045279.
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Durgan, K. et al. (2010). Targeting NKT cells and PD-L1 pathway results in augmented anti-tumor responses in a melanoma model. Cancer Immunol Immunotherapy 10.1007/s00262-010-0963-5.
Fletcher, A. et al. (2010). Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions JEM 207, 689.
Kelly, R. et al. (2010). Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation. Blood 115, 1088.
Ordaz, M. et al. (2010). DC-expressed MHC class I single-chain trimer-based vaccines prime cytotoxic T lymphocytes against exogenous but not endogenous antigens. Cell Immunol 262, 141.
Sun X. et al. (2010). Enhanced in vivo gene expression mediated by listeriolysin o incorporated anionic LPDII: Its utility in cytotoxic T lymphocyte-inducing DNA vaccine. J Control Release 10.1016/j.jconrel.2010.06.017.
Nakayama, M. et al. (2009). Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation. Blood 113, 3821.
Peng, Y. et al. (2009). Ly6Clow monocytes differentiate into dendritic cells and cross-tolerize T cells through PDL-1. Blood 182, 2777.
Qu, C. et al. (2009). MHC class I/peptide transfer between dendritic cells overcome poor cross-presentation by monocyte-derived APCs that engulf dying cells. J Immunol 182, 3650.
Kelly, RM. et al. (2008). Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation. Blood 111, 5734.
Towne, CF. et al. (2008). Puromycin-sensitive aminopeptidase limits MHC class I presentation in dendritic cells but does not affect CD8 T cell responses during viral infections. J Immunol 180, 1704.
Kislin, KL. et al. (2007). Chaperone-rich cell lysate embedded with BCR-ABL peptide demonstrates enhanced anti-tumor activity against a murine BCR-ABL positive leukemia. FASEB J 21, 2173.
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Cante-Barnett, K. et al. (2006). Thymocyte negative selection is mediated by protein kinase C-and Ca2+ -dependent transcriptional induction of Bim. J Immunol 176, 2299.
Ren, Y. et al. (2006). OVA-specific CD8+T cells do not express granzyme B during anterior chamber associated immune deviation. Graefe's ARch Clin Exp Ophthalmol 244, 1315.
Galibert, L. et al. (2005). Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule. J Biol Chem 280, 21955.
Komlosh, A. et al. (2001). A role for a novel luminal endoplasmic reticulum aminopeptidase in final trimming of 26 S proteasome-generated major histocompatability complex class I antigenic peptides. J Biol Chem 276, 30050.
Ben-Shahar, S. et al. (1999). 26 S proteasome-mediated production of an authentic major histocompatibility classI-restricted epitope from an intact protein substrate. J Biol Chem 274, 21963.
Ben-Shahar, S. et al. (1997). Production of a specific major histocompatibility complex class I-restricted epitope by ubiquitin-dependent degradation of modified ovalbumin in lymphocyte lysate. J Biol Chem 272, 21060.
Lyszkiewicz, M. et al. (2011). SIGN-R1+MHC II+ cells of the splenic marginal zone—a novel type of resident dendritic cells. J Leukocyte Biol89 607. doi: 10.1189/jlb.0610368.
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