This is caspase 6 substrate that recognizes VEID residues and cleaves lamin. This is a fluorogenic product labeled with 7-methoxy coumarin, which enables this peptide to have applications in protein-protein interaction and localization studies.
Nagata S. et al. Cell 88:355-365 (1997).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
Mca - Val - Gln - Val - Asp - Gly - Trp - Lys(Dnp) - NH2