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Peptides  >  HIV Related Peptides  >>  TAT (47-57) GGG-Cys(Npys)

Product Name TAT (47 - 57) GGG - Cys(Npys)
YGRKKRRQRRRGGG - C(Npys) - NH2
Size 1 mg
Catalog # AS-61215
US$ $242
Description

This peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. The N-terminus is rendered free for applications requiring certain conjugation reactions with a free N-terminal end, and a linker GGG is placed at the C-terminal end, and the peptide has been synthesized with the C(Npys) group. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.

Storage -20C
References 1, Bright R. et al. Neurosci lett. 441, 120-124 (2008)
2, Moultin HM. et al. Bioconj Chem. 15(2):290-299 (2004).
Molecular Weight 1987.3
Sequence
(One-Letter Code)
YGRKKRRQRRRGGG-C(Npys)-NH2
Sequence
(Three-Letter Code)
H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Gly - Gly - Gly - Cys(NPYS) - NH2
     
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