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Peptides  >  Kinases/Phosphatase Substrates  >  CDK5 (Cyclin-dependent Kinase 5)  >>  CDK5 Substrate [PKTPKKAKKL]

Product Name CDK5 Substrate [PKTPKKAKKL]
PKTPKKAKKL
Size 5 mg
Catalog # 60026-5
US$ $407
Purity % Peak Area By HPLC ≥ 95%
Description

The native peptide PKTPKKAKKL (60026-1) is derived from histone H1 peptide sequence that is docked in the active site of cyclin-dependent kinase 5. It is an effective CDK5 substrate (Km = 40 M).

Detailed Information Datasheet
Storage -20C
References Ref: Lew, J. Biochem. 42, 849 (2003); Sharma, P. et al. J. Biol. Chem. 274, 9600 (1999).
Molecular Weight 1138.5
Sequence
(One-Letter Code)
PKTPKKAKKL
Sequence
(Three-Letter Code)
H - Pro - Lys - Thr - Pro - Lys - Lys - Ala - Lys - Lys - Leu - OH
Product Citations Liu, M. et al. (2010). Kinetic Mechanistic Studies of Cdk5/p25-Catalyzed H1P Phosphorylation: Metal Effect and Solvent Kinetic Isotope Effect. Biochem 49, 4921.
     
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