This 29 amino acid sheep myeloid antimicrobial peptide 29 (SMAP 29) displays extremely high antimicrobial activity against Pseudomonas strains, other gram-negative bacteria, and multidrug-resistant pathogens. SMAP 29 is a broad-spectrum antibiotic cathelicidin, it is active in both low- and high-ionic-strength conditions, and induces significant morphological alterations in bacterial surfaces.
Saiman, L. et al. Antimicrob. Ag. Chemother. 45, 2838 (2001).
Molecular Weight
3256
Sequence (One-Letter Code)
RGLRRLGRKIAHGVKKYGPTVLRIIRIAG
Sequence (Three-Letter Code)
H - Arg - Gly - Leu - Arg - Arg - Leu - Gly - Arg - Lys - Ile - Ala - His - Gly - Val - Lys - Lys - Tyr - Gly - Pro - Thr - Val - Leu - Arg - Ile - Ile - Arg - Ile - Ala - Gly - OH
Datasheet
