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Peptides  >  Neuropeptides  >>  NPVF

Product Name NPVF
VPNLPQRF - NH2
Size 1 mg
Catalog # AS-62006
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

This sequence is a neuropeptide encoded by the NPVF gene. The NPVF-is the endogenous ligand for FF1 receptor. NPVF mRNA was detected specifically in a region between the dorsomedial and ventromedial hypothalamic nuclei. Following intracerebral administration, NPVF-derived peptide blocks morphine-induced analgesia in both acute and inflammatory models of pain. The NPVF/FF1 system may be an important part of endogenous anti-opioid mechanism.

Storage -20C
References Liu, Q. et al. J. Biol. Chem. 276, 36961 (2001).
Molecular Weight 969.2
Sequence
(One-Letter Code)
VPNLPQRF-NH2
Sequence
(Three-Letter Code)
H - Val - Pro - Asn - Leu - Pro - Gln - Arg - Phe - NH2
Product Citations Cline, M. et al. (2009). Neuropeptide VF-associated satiety involves mu and kappa but not delta subtypes of opioid receptors in chicks. Neurosci Lett 455, 195.
     
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