The native peptide, PLSRTLSVAAKK-NH2 (cat# 27177), is a synthetic substrate partially derived from a sequence in glycogen synthase. It is an effective substrate for CaM kinase II and protein kinase C (PKC). It is readily phosphorylated by PKC (Km = 4.1 µM).
Ref: Alexander, DR. et al. Biochem. J. 268, 303 (1990); House, C. et al. J. Biol. Chem. 262, 772 (1987). Pearson, RB. et al. J. Biol. Chem. 260, 14471 (1985).
Molecular Weight
1269.6
Sequence (One-Letter Code)
PLSRTLSVAAKK-NH2
Sequence (Three-Letter Code)
H - Pro - Leu - Ser - Arg - Thr - Leu - Ser - Val - Ala - Ala - Lys - Lys - NH2