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Peptides  >  Signal Transduction Peptides  >>  Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled

Product Name Steroid Receptor Coactivator - 1 (SRC - 1), (676 - 700), biotin labeled
Biotin - CPSSHSSLTERHKILHRLLQEGSPS
Size 1 mg
Catalog # AS-62152
US$ $242
Purity % Peak Area By HPLC ≥ 95%
Storage -20C
References This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminnaly biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain.
Molecular Weight 3026.5
Sequence
(One-Letter Code)
Biotin-CPSSHSSLTERHKILHRLLQEGSPS
Sequence
(Three-Letter Code)
Biotin - Cys - Pro - Ser - Ser - His - Ser - Ser - Leu - Thr - Glu - Arg - His - Lys - Ile - Leu - His - Arg - Leu - Leu - Gln - Glu - Gly - Ser - Pro - Ser - OH
     
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