Drosocin is a 19-mer cationic antimicrobial peptide from Drosophila melanogaster. In Drosophila native drosocin carries a disaccharide moiety attached to a threonine residue in mid-chain position. This synthetic drosocin peptide of identical amino acid sequence without the disaccharide has an activity several times lower than the native compound.
Bikker, F. et al. Chemical Biology & Drug Design 68, (2006), Bulet, P.et al. Eur. J. Biochem. 238, 64 (1996). Bulet, P.et al. J. Biol. Chem. 268, 14893 (1993).
Molecular Weight
2198.6
Sequence (One-Letter Code)
GKPRPYSPRPTSHPRPIRV
Sequence (Three-Letter Code)
H - Gly - Lys - Pro - Arg - Pro - Tyr - Ser - Pro - Arg - Pro - Thr - Ser - His - Pro - Arg - Pro - Ile - Arg - Val - OH
Datasheet
