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Peptides  >  Cancer Research Peptides  >>  Bax H2-H3 (53-86), Helix 2-3

Product Name Bax H2 - H3 (53 - 86), Helix 2 - 3
DASTKKLSECLKRIGDELDSNMELQRMIAAVDTD
Size 1 mg
Catalog # 62283
US$ $291
Purity % Peak Area By HPLC ≥ 95%
Description

This Bax H2-H3 peptide is amino acids 53 to 86 fragment of Bax which contains the BH3 helix plus residues in the downstream helix 3 (amino acids 7481). Cultured cells injected with the H2-H3 peptide result in morphological changes consistent with apoptosis, including plasma membrane blebbing. H2-H3 peptide mimics Bax auto-activation.

Storage -20C
References Tan, C. et al. J. Biol. Chem 281, 14764 (2006).
Molecular Weight 3797.3
Sequence
(One-Letter Code)
DASTKKLSECLKRIGDELDSNMELQRMIAAVDTD
Sequence
(Three-Letter Code)
H - Asp - Ala - Ser - Thr - Lys - Lys - Leu - Ser - Glu - Cys - Leu - Lys - Arg - Ile - Gly - Asp - Glu - Leu - Asp - Ser - Asn - Met - Glu - Leu - Gln - Arg - Met - Ile - Ala - Ala - Val - Asp - Thr - Asp - OH
     
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