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Peptides  >  Signal Transduction Peptides  >>  WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist

Product Name WRW4, Formyl Peptide Receptor - Like 1 (FPRL1) Antagonist
WRWWWW
Size 1 mg
Catalog # AS-62638
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.

Storage -20C
References Bae, Y-S. et al. J. Immunol. 173, 607 (2004).
Molecular Weight 1105.3
Sequence
(One-Letter Code)
WRWWWW
Sequence
(Three-Letter Code)
H - Trp - Arg - Trp - Trp - Trp - Trp - OH
Product Citations Seidel, S. et al. (2012). Annexin A1 modulates macula densa function by inhibiting cyclooxygenase 2. Am J Physiol Renal Physiol 303, F845. doi: 10.​1152/​ajprenal.​00704.​2011.
Byfield, FJ. et al. (2011). Cathelicidin LL-37 increases lung epithelial cell stiffness, decreases transepithelial permeability, and prevents epithelial invasion by Pseudomonas aeruginosa. J Immunol 187, 640. doi: 10.4049/​jimmunol.1102185 (2011).
     
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