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Recombinant Proteins  >  HCV (Hepatitis C Virus)  >>  HCV NS3/4A protease mutant A156S, recombinant

Product Name HCV NS3/4A protease mutant A156S, recombinant
Size 5 ug
Catalog # 72022-5
US$ $247
Description

The recombinant HCV NS3/4A protease mutant A156S is derived from its wild type (NCBI Accession: CAB46913) with a substitution of Ala156 with Ser. This single mutation is reported to be responsible for the resistance to VX-950, a potent HCV NS3/4A protease inhibitor tested in phase I clinical trial. But this mutant remains sensitive to BILN2061, another potent HCV NS3/4A protease inhibitor. This mutated form is important to be tested when screening for new HCV NS3/4A protease inhibitors.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
     
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