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Peptides  >  Histones  >  Histone Related Substrates  >>  AKT/PKB/Rac-Protein Kinase Substrate [ARKRERTYSFGHHA], Biotinylated

Product Name AKT/PKB/Rac - Protein Kinase Substrate [ARKRERTYSFGHHA], Biotinylated
Biotin - ARKRERTYSFGHHA
Size 1 mg
Catalog # AS-29945-1
US$ $143
Purity % Peak Area By HPLC ≥ 95%
Description

The native peptide ARKRERTYSFGHHA (29944-1) is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 M). It also competitively inhibits histone H2B phosphorylation (Ki = 12 M) by AKT.

Storage -20C
References Obata, T. et al. J. Biol. Chem. 275, 36108 (2000). Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).
Molecular Weight 1942.2
Sequence
(One-Letter Code)
Biotin-ARKRERTYSFGHHA
Sequence
(Three-Letter Code)
Bioton - Ala - Arg - Lys - Arg - Glu - Arg - Thr - Tyr - Ser - Phe - Gly - His - His - Ala - OH
Product Citations Peng, C. et al. (2007). Pim kinase substrate identification and specificity. J. Biochem.141, 353.
     
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